Post-Vent, the Sequelae: Personalized Prognostic Modeling for Consequences of Neonatal Intermittent Hypoxemia in Preterm Infants at Pre-School Age

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

Despite improved survival of extremely premature infants in recent decades, neonatal intensive care unit (NICU) graduates are diagnosed with asthma, sleep disordered breathing (SDB) in childhood, and neurodevelopmental impairments (NDI) at significant rates, disproportionate to their term peers. Early detection and intervention are critical to mitigate the impact of these impairments. Mechanisms leading from premature birth to these undesirable outcomes remain unclear, and accurate prognostic measures are lacking. This study wants to learn if these problems are related to certain patterns of breathing that babies had while they were in the NICU.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 7 months
Maximum Age: 6
Healthy Volunteers: f
View:

• Enrolled in any Institutional Review Board (IRB) protocol of the Pre-Vent Study that had signed consent, or in any IRB protocol of the Pre-Vent Study that authorized re-contact for future research

• Born \<29 weeks gestational age

• Age at enrollment less than 7 years old

Locations
United States
Illinois
Ann & Robert H. Lurie Children's Hospital of Chicago
RECRUITING
Chicago
Contact Information
Primary
Erin Smith Lonergan
ersmith@luriechildrens.org
312-227-3300
Backup
Casey Rand
crand@luriechildrens.org
312-227-3300
Time Frame
Start Date: 2022-11-01
Estimated Completion Date: 2026-06-30
Participants
Target number of participants: 500
Sponsors
Collaborators: Northwestern University, University of Miami, University of Virginia, University of Alabama at Birmingham, Case Western Reserve University, National Heart, Lung, and Blood Institute (NHLBI)
Leads: Ann & Robert H Lurie Children's Hospital of Chicago

This content was sourced from clinicaltrials.gov